VNOTES and Vaginal Hysterectomy for Benign Indications

Republic of Turkey Ministry of Health

Status: Not yet enrolling

Conditions: Hysterectomy, Vaginal; Hysterectomy, Benign Uterine Diseases; Hysterectomy

Treatments: Procedure: vaginal hysterectomy; Procedure: vNOTES

Study type: Interventional

Funder types: Other

Identifiers

NCT06776718

2021/514/214/25

Details and patient eligibility

About

This study aimed to compare the surgical outcomes of Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) and conventional vaginal hysterectomy (VH) for benign gynecological conditions.

A prospective analysis will conducted at a tertiary hospital from January 2025 to February 2025. Patients aged 40-80 who underwent hysterectomy for benign indications will included. Outcomes will assessed included surgical outcomes, Visual Analog Scale (VAS) pain scores, and complication rates.

Enrollment: 100 estimated patients

Sex: Female

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• aged between 40 and 80 years
• undergo hysterectomy for benign gynecological conditions

Exclusion criteria

• history of urogynecological surgery (including pelvic organ prolapse surgery and mid-urethral sling procedures),
• suspected gynecologic malignancies,
• endometriosis,
• tubal-ovarian abscesses,
• pelvic organ prolapse exceeding grade 2,
• individuals who refused to participate in the study

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

vNOTES hysterectomy for benign indications

Experimental group

Treatment:

Procedure: vNOTES

Vaginal hysterectomy for benign indications

Experimental group

Treatment:

Procedure: vaginal hysterectomy