Voice Analysis Using the LPC (Linear Predictive Coding)Method for the Prediction of Aspiration

Ulsan University Hospital

Status: Withdrawn

Conditions: Deglutition Disorder

Treatments: Device: VFSS

Study type: Interventional

Funder types: Other

Identifiers

NCT01981239

chhwang4

Details and patient eligibility

About

It was well known that aspiration is the primary cause of an aspiration pneumonia among the dysphagia patients.

In order to predict the degree of an aspitation,video-fluoroscopic-swallowing study and fiberoptic-endoscopic swallowing evaluation have been developed, but those evaluations are invasive and allowed only in a limited condition.

In this study, as a precedent study for the non-linear analysis, voice analysis using LPC method will be evaluated. The superiority of LPC method will be compared with a spectral analysis using Jitter and Simmer as a positive control.

This clinical study will be performed prospective, positive-controlled, single-blind (i.e. assessor-blind),and single cohort clinical trial for efficacy

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who were referred for VFSS

Exclusion criteria

• Patients cannot phonate d/t tracheostomy
• Preexisting oro-laryngo-pharyngeal disease
• Patients cannot follow 1 step command
• Patients cannot maintain a phonation for 3 seconds
• Refusal of participation
• Patients who were not classified for the candidate by physicians
• Patients who coughs following drinking of 5ml normal saline

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

LPC analysis group

Experimental group

Description:

Voice sampling is executed before and immediately after drinking of 20ml N/S and linear voice analyses using LPC method are performed to calculate LPC index, residual variance, coefficiency mean, coeffiency variance, and coeffiency skewness.

Treatment:

Device: VFSS

spectral analysis group

Active Comparator group

Description:

Voice sampling is executed before and immediately after drinking of 20ml N/S and spectral voice analyses using Dr. Speech program are performed to calculate HNR (dB), RAP (%: Jitter), Mean and SD Fundamental Frequency (Hz: Fo), Shimmer (%) and SNR (dB).

Treatment:

Device: VFSS