Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures

Centre d'Investigation Clinique et Technologique 805

Status: Terminated

Conditions: Respiratory Failure; Neuromuscular Diseases

Treatments: Other: Phrenic nerves magnetic stimulations

Study type: Interventional

Funder types: Other

Identifiers

NCT02078050

2013-A00638-37

Details and patient eligibility

About

Respiratory failure is the main death cause in neuromuscular diseases. Non-invasive and volitional measures of inspiratory muscles strength include the nasal pressure with an occluded nostril (Psnip) and the maximal inspiratory pressure (PImax). Unfortunately, volitional maneuvers depend of patient effort. The aim of this research is to validate a non-invasive and non-volitional technique to evaluate diaphragm strength at neuromuscular diseases patients. The methodology consists to add to PImax and Psnip measures 5 phrenic nerves magnetical stimulation maneuvers (Pstim).Stimulations will be realize at 3 inspiratory pression levels (0, -1 cm H2O and -5 cm H2O).

Enrollment: 54 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years old and more men or women
• neuromuscular diseases
• Pimax and Snip evaluation Indication

Exclusion criteria

• pregnant women
• Usual contre-indications for nuclear magnetic resonance

Trial design

54 participants in 1 patient group

Phrenic nerves magnetic stimulations

Other group

Treatment:

Other: Phrenic nerves magnetic stimulations