Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Alexandria University

Status and phase: Completed; Early Phase 1

Conditions: Necrotic Pulp; Periapical; Infection

Treatments: Other: Regenerative Endodontics Procedures (REPs)

Study type: Interventional

Funder types: Other

Identifiers

NCT04646538

19832009

Details and patient eligibility

About

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

Full description

REPs were done for 10 mature maxillary necrotic teeth with periapical lesions confirmed by digital periapical radiographs. Instrumentation was done using Protaper Next till size X3 (size 30). Pre-operative radiographs also included CBCT scans to measure the 3D volume and area of the periapical lesion to be used as baseline data. The postoperative radiographic examination included: a) digital periapical radiographs taken at 3,6,9, and 12 months to monitor the lesion through out the follow-up period. b)CBCT scan to measure quantitatively the volume and area of the periapical lesion after 12 months follow up

Enrollment: 10 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Necrotic Mature Maxillary anterior teeth with periapical lesions.

Exclusion criteria

• Patients with mobile and fractured teeth

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

X3 group

Experimental group

Treatment:

Other: Regenerative Endodontics Procedures (REPs)