Volume Controlled Ventilation vs Autoflow-volume Controlled Ventilation (VCVAFVCV)

Korea University

Status: Withdrawn

Conditions: Prostate Cancer

Treatments: Device: autoflow-volume controlled ventilation; Device: volume controlled ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT02512120

Autoflow46

Details and patient eligibility

About

Volume controlled ventilation(VCV) is a most common used ventilation mode during general anesthesia. But VCV can cause high airway peak pressure when patient under steep Trendelenberg position with pneumoperitoneum. Autoflow-VCV can reduce airway peak pressure and improve dynamic compliance. We will compare parameters(arterial blood gas analysis, airway compliance, etc) when each group applied VCV and autoflow-VCV during RALP.

Full description

Robot assisted laparoscopic radical prostatectomy(RALP) has been used to treatment of prostate cancer since 2001. RALP offers some advantage such as reduced blood loss, sparing nerves, less postoperative pain. However, RALP require steep Trendelenberg position with pneumoperitoneum. It can cause increased airway peak pressure and unwanted hemodynamic effect under conventional volume controlled ventilation(VCV). Autoflow-VCV use decelerating flow, can reduce airway peak pressure and improve dynamic compliance.

We will compare parameters(arterial blood gas analysis, airway compliance, etc) when each group applied VCV and autoflow-VCV during RALP.

Sex: Male

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (age 19-65)
• American Society of Anesthesiology Classification I-III

Exclusion criteria

• cardiovascular disease, cerebrovascular disease, pulmonary disease
• over BMI 30

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

volume controlled ventilation

Experimental group

Description:

Randomized 23 patients will be applied VCV during RALP.

Treatment:

Device: volume controlled ventilation

autoflow-volume controlled ventilation

Active Comparator group

Description:

Randomized 23 patients will be applied autoflow-VCV during RALP.

Treatment:

Device: autoflow-volume controlled ventilation