Volume Parameters vs Flow Parameters in Assessment of Reversibility in Chronic Obstructive Pulmonary Disease

Assiut University

Status

Unknown

Conditions

Chronic Obstructive Pulmonary Disease

Treatments

Diagnostic Test: Whole body plethysmography

Study type

Interventional

Funder types

Other

Identifiers

NCT03282526

PFTs in COPD

Details and patient eligibility

About

Assess the differences between flow and volume responses after bronchodilator reversibility testing in patients over different clinical chronic obstructive pulmonary disease stages (GOLD stage I to GOLD stage IV).
Study the Correlation between the bronchodilator response and the severity of the disease.

Full description

chronic obstructive pulmonary disease is a common preventable and treatable disease characterized by persistent airflow limitation that is usually progressive. The diagnosis requires an evidence of obstructive pattern by spirometry measured before and after bronchodilators.

The degree of reversibility of airflow obstruction differs between patients, and does not predict the response to bronchodilator therapy. It can be seen in terms of forced vital capacity (FVC) or forced expiratory volume in the first second (FEV1),or Inspiratory capacity (IC) or residual volume (RV).

Enrollment

100 estimated patients

Sex

All

Ages

40 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients Clinical diagnosis of Chronic Obstructive Pulmonary Disease
Must be able to do pulmonary function test
Age more than 40 years
Stable Chronic Obstructive Pulmonary Disease patients

Exclusion criteria

Any patients with a diagnosis of:

Bronchial asthma
Bronchiectasis
Respiratory failure
Decompensated core pulmonale
Chronic Obstructive Pulmonary Disease combined with any other respiratory disease