Volumetric Monitoring in Major Lung Surgery (EVLW-PNEUMO)

Northern State Medical University

Status: Completed

Conditions: Pneumonectomy; Acute Pulmonary Edema

Study type: Observational

Funder types: Other

Identifiers

NCT01455766

2005-2011

Details and patient eligibility

About

The hypothesis of this observational single-center clinical study was to explore the volumetric hemodynamic monitoring in the perioperative period in major and risky thoracic intervention. The investigators monitored the changes in the volumes of blood in the central vessels and heart chambers as well as a volume of fluid in pulmonary tissue (i. e. extravascular lung water).

Full description

The goal of this observational study is to investigate into changes in volumetric hemodynamic parameters obtained with a technique of transpulmonary indicator dilution after major thoracic intervention, including pneumonectomy and lobar resections. The important parameters of hemodynamics were monitored throughout the intervention and 48 hrs postoperatively, including extravascular lung water index, global end-diastolic volume index, etc.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent
• Age above 18 and below 80
• Confirmed malignant bronchial neoplasm or
• Destructive pulmonary infection

Exclusion criteria

• Pregnant
• Severe pulmonary hypertension
• Pulmonary tuberculosis
• Severe occlusive atherosclerosis of lower extremities