Vulvar Scarring Grading Scale for Lichen Sclerosus

Northwestern University

Status: Terminated

Conditions: Lichen Sclerosus; Lichen Sclerosus et Atrophicus

Treatments: Other: Photography

Study type: Observational

Funder types: Other

Identifiers

NCT02880904

STU00202270

Details and patient eligibility

About

The study aims to validate a vulvar scarring grading scale for lichen sclerosus (LS).

Full description

Utilizing the vulvar disorders registry, protocol #STU00001056, the research team seeks to analyze the medical record data, including standard of care vulvar photographs, of the vulvar LS population at Northwestern Memorial Hospital (NMH) and the outpatient clinics of Northwestern Medicine (NM). These photographs will be used to develop a vulvar scarring grading scale for LS. The objective measurement of scarring severity in LS deidentified standard-of-care patient photographs will be correlated with clinical examination findings to assess validity of the grading scale. The development of an objective and standardized grading scale will assist with the longitudinal evaluation of individual disease, assessment of impact of therapy on scarring, and inform treatment modifications. Further, objective grading of scarring would also provide the opportunity to search for potential correlation between QoL scores and severity of clinical states in scarring dermatoses.

Enrollment: 30 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients seen at Northwestern Medicine Department of Dermatology and/or Department of Obstetrics and Gynecology, who were seen by Dr. Bethanee Schlosser, and/or other members of the Vulvar Mucosal Specialty Clinic team in any of their respective clinic settings and underwent complete mucocutaneous examination.
• Patients with histologically confirmed vulvar LS.

Exclusion criteria

• Patients who refuse complete mucocutaneous examination.
• Patients who refuse recommended diagnostic procedures.
• Pregnant women or prisoners.