Novel Imaging Biomarkers for Mechanical Complications in Acute Myocardial Infarction (MIRON-RUPTURE)

Rohan Dharmakumar

Status: Completed

Conditions: Myocardial Stunning; Myocardial Hemorrhage; Hemorrhagic Myocardial Infarction; Myocardial Reperfusion Injury; Myocardial Rupture (Post Infarct); Acute Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT06450912

19978e

Details and patient eligibility

About

Hemorrhagic Myocardial infarctions are at high risk for mechanical complications including cardiac rupture. Prediction of vulnerable myocardial segments is an important step for the stratification of hemorrhagic MI patients. Wall motion index ratio is an important parameter to determine regions of high vulnerability within the 17-segment LV model of hemorrhagic MI.

Enrollment: 250 patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Index STEMI
• Primary PCI
• Able to complete Cardiac MR - STRAIN Protocol

Exclusion criteria

• Contraindication to CMR (Contrast Hypersensitivity, Metallic Implants, Abnormal Rhythms, breathing difficulties)