Warm Patch Decrease Propofol Injection Pain

First People's Hospital of Chenzhou

Status: Completed

Conditions: Propofol Infusion Syndrome; Pain Syndrome; Injection Site Irritation

Treatments: Device: Cotton patch; Device: Warming patch

Study type: Interventional

Funder types: Other

Identifiers

NCT04555980

202001

Details and patient eligibility

About

Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection. Using an air warmer to warm the arm can also reduce the pain caused by propofol injection. Investors suspect that treatment with a warming patch (covering the injection site) can also reduce the pain caused by propofol injection.

Full description

This is a single-center randomized controlled clinical study. Purpose of this study is to explore whether the coverage of the warming patch (for 5min before injection) can reduce the pain induced by propofol injection.

The patients included in the study were randomly divided into two groups. The group W used a warming patch to cover the injection site, and the group C used a cotton pad to cover the injection site. After 5 minutes of coverage, the propofol injection was induced, and the patient's complaint of pain (calling or arm withdrawal) during propofol injection was observed, and the patient's recall of the pain score during induction after the patient recovered. After the patients regained consciousness, the data of the two groups were compared to determine whether the use of the warming patch could reduce the pain caused by propofol injection.

Enrollment: 120 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No peripheral phlebitis
• No history of Raynaud's syndrome
• No history of smoking or alcoholism
• Body mass index BMI<28 kg/cm2

Exclusion criteria

• Refusal of anesthesia
• Previous injection pain caused by propofol
• Difficulty in exposing the veins on the back of the hand or difficulty in venipuncture
• Complained of pain after normal saline infusion.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups, including a placebo group

Warm patch

Experimental group

Description:

the injection site was covered with warm patch.

Treatment:

Device: Warming patch

Cotton patch

Placebo Comparator group

Description:

the injection site was covered with cotton patch.

Treatment:

Device: Cotton patch