Warm Water Versus Room Temperature Water Immersion Colonoscopy

Vitkovice Hospital

Status: Completed

Conditions: Colorectal Cancer

Treatments: Procedure: Cool Water Immersion Colonoscopy; Procedure: Warm Water Immersion Colonoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT01582178

DDC VN 04

Details and patient eligibility

About

Water immersion insertion has been documented to decrease procedure-related discomfort during colonoscopy. There was used warm water infusion for colonoscope insertion in most of the water immersion colonoscopy trials.

The investigators have been using room temperature water (20-24°C) for water immersion and the investigators did not notice any drawback of it. In our opinion, it is simpler and cheaper option for water immersion colonoscopy and proof of its efficacy and safety could support the use of water immersion technique in routine practice.

The primary endpoint is cecal intubation time and the investigators suppose that the use of warm water infusion does not shorten it significantly. Patient comfort during colonoscope insertion, water consumption, length of the scope while reaching the cecum, need for external compression, need for positioning of the patient and endoscopist´s difficulty with colonoscopy will be also assessed.

Enrollment: 212 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• outpatient diagnostic colonoscopy
• bowel prep with macrogolum
• initial 2 mg of midazolam i.v.
• signed informed consent form

Exclusion criteria

• planned therapeutic intervention
• colorectal surgery in history
• known inflammatory bowel disease or colorectal cancer
• refusal of sedation

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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212 participants in 2 patient groups

Warm Water Immersion Colonoscopy

Experimental group

Description:

Colonoscopy using purely warm water (37°C) infusion during colonoscope insertion and room air insufflation during colonoscope withdrawal.

Treatment:

Procedure: Warm Water Immersion Colonoscopy

Cool Water Immersion Colonoscopy

Active Comparator group

Description:

Colonoscopy using purely room temperature water (20-24°C) infusion during colonoscope insertion and room air insufflation during colonoscope withdrawal.

Treatment:

Procedure: Cool Water Immersion Colonoscopy