ClinicalTrials.Veeva

Menu

WASH Benefits Child Development Follow up (WASH-BFU)

I

International Centre for Diarrhoeal Disease Research (icddr,b)

Status

Unknown

Conditions

Child Development
Maternal Depression

Treatments

Behavioral: Water quality
Behavioral: Sanitation
Behavioral: Hand washing
Behavioral: Nutrition, Water quality, Sanitation, Hand washing
Behavioral: Nutrition
Behavioral: Water quality, Sanitation, Hand washing (Combined WASH)

Study type

Interventional

Funder types

Other

Identifiers

NCT04443855
PR-19025

Details and patient eligibility

About

The purpose of this study is to determine if the effects of individual and combined water, sanitation, hygiene, and nutrition interventions in early childhood on child development and maternal mental health persist into middle childhood. This study is a follow-up assessment of the children and mothers enrolled in the WASH-Benefits Bangladesh study.

Full description

Globally, millions of children experience delays in physical health and cognitive development, due to their exposures to poverty and related issues. In low-and middle-income countries, children experience a dis-proportionally high burden of exposure to poverty and related risk factors for delayed development including of poor health and nutrition, inadequate responsive care giving, and a lack of opportunities for early learning. Water, sanitation and hygiene (WASH) interventions have the potential to positively affect the developmental trajectories of children by reducing enteric pathogen infection, improving child health, and altering parental care practices. A recent cluster-randomized controlled trial (cRCT) in Bangladesh (WASH-Benefits, or WASH-B, Clinical Trials.gov Identifier: NCT01590095), found that improvements in WASH or nutrition supported by intensive interpersonal communication, when delivered either individually or in combination, contributed to improvements in child development outcomes at 1 and 2 years of age, and mothers in all intervention groups reported lower depressive symptoms than mothers in the control households.

This follow-up study, funded by the Bill & Melinda Gates foundation, includes assessments of the children and caregivers originally enrolled in the WASH Benefits intervention 5 years following intervention completion, when the children are 5-8 year of age. The original WASH Benefits intervention enrolled pregnant women between May 31, 2012, and July 7, 2013. The goal of this follow-up study is to examine whether the improvements in child development and maternal mental health are sustained when the children are in middle childhood. Our guiding hypothesis is that interventions that showed early impact will continue to improve child and maternal outcomes at this follow-up time period. Investigators will attempt to collect follow-up data from every household originally randomized to one of the 7 arms in the WASH Benefits trial.

Enrollment

4,932 estimated patients

Sex

All

Ages

5 to 7 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Enrolled in the wash-benefits Bangladesh intervention

Exclusion criteria

  • No Exclusion criteria

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

4,932 participants in 7 patient groups

Water quality
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Water quality
Sanitation
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Sanitation
Hand washing
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Hand washing
Combined WASH
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Water quality, Sanitation, Hand washing (Combined WASH)
Nutrition
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Nutrition
Nutrition+ Combined WASH
Active Comparator group
Description:
90 clusters, approx. 720 newborns
Treatment:
Behavioral: Nutrition, Water quality, Sanitation, Hand washing
Non-intervention
No Intervention group
Description:
180 clusters, approx. 1,440 newborns

Trial contacts and locations

1

Loading...

Central trial contact

Mahbubur Rahman, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems