Wastewater Surveillance to Boost COVID-19 Vaccine Uptake

Syracuse University

Status: Completed

Conditions: Wastewater Surveillance; Vaccination

Treatments: Behavioral: Wastewater vaccine prompts

Study type: Interventional

Funder types: Other

Identifiers

NCT05766189

BOOST-wastewater

Details and patient eligibility

About

The goal of the study is to determine the effect of a communications campaign sharing wastewater surveillance data to influence vaccine uptake in a metropolitan and non-metropolitan environment. The study will be conducted in Onondaga and Cayuga counties in New York State. Individuals of all ages within the selected counties, located in metropolitan and non-metropolitan environments will receive the intervention. The evaluation study design is a comparison-control trial. The primary outcome measure is the proportion of vaccine-eligible individuals in the county that received the COVID-19 vaccine stratified by type of vaccine dosage and age group. Vaccination data will be aggregated to the county by the State Department of Health and shared with the research team. Wastewater data will be pulled from the wastewater surveillance network. A difference in differences analysis will be used to estimate the effect of the intervention on both the outcomes between intervention and comparison groups following the intervention, while adjusting for potential confounding factors.

Enrollment: 100,000 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• None - county-level vaccine uptake - no direct interaction with people getting vaccines

Exclusion criteria

• None

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100,000 participants in 2 patient groups

Intervention arm

Experimental group

Description:

Receives communications on level of SARS-CoV-2 as identified in the wastewater

Treatment:

Behavioral: Wastewater vaccine prompts

Comparison arm

No Intervention group