Waterjet Versus Ultrasound Dissection During Hepatic Transection

Karolinska University Hospital

Status and phase: Completed; Phase 2

Conditions: Liver Tumour

Treatments: Device: CUSA induced dissection; Device: Waterjet induced dissection

Study type: Interventional

Funder types: Other

Identifiers

NCT02041065

2011/2:4

2011/2.4 (Other Identifier)

Details and patient eligibility

About

Before liver transection patients are allocated to either waterjet or CUSA to divide the liver parenchyma.

Full description

Transection time, bloodloss, total operation time and postoperative complication rates are registered.

Enrollment: 84 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hepatic tumour suitable for resection
• patients 18 year or older Segmental resection Local resection Left sided hemihepatectomy

Exclusion criteria

• Right sided hemihepatectoyReresection In Situ Split Liver Extended left- and rightsided hemihepatectomy Lobus caudatus resection Central resections Hilus tumour/Klatskin/Cholangiocarcinoma Surgery on biliary tree Extended resection on other organs

Resection on gallbladder Resection on other organs during the same operation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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84 participants in 2 patient groups

Waterjet induced dissection

Experimental group

Description:

Waterjet induced dissection of the liver during resection.Waterjet dissection device mechanically separates hepatic tissue from bile ducts and vessels, the latter two to be separately ligated.

Treatment:

Device: Waterjet induced dissection

CUSA induced dissection

Active Comparator group

Description:

CUSA transection of the liver. Ultrasound based destruction of the liver parenchyma to allow separate ligation of the bile duct and intrahepatic vessels.

Treatment:

Device: CUSA induced dissection