Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults (WAVE)

Brian Driver

Status: Not yet enrolling

Conditions: Acute Respiratory Failure

Treatments: Diagnostic Test: Colorimetric carbon dioxide (CO2) detection; Diagnostic Test: Waveform capnography

Study type: Observational

Funder types: Other

Identifiers

NCT06934876

IRB-FY2024-947

Details and patient eligibility

About

This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.

Enrollment: 1,332 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patient is located in a participating unit (ED or ICU)
2. Patient is undergoing tracheal intubation.
3. The clinician intends to use an exhaled CO2 detection device to confirm tracheal placement of the tube.

Exclusion criteria

1. Patient is known to be a prisoner
2. Patient is known to be < 18 years old
3. A responsible clinician has determined that sole use of either waveform capnography or colorimetric testing is required for optimal care of the patient.

Trial design

1,332 participants in 1 patient group

Critically ill adults undergoing emergency tracheal intubation

Description:

Adult patients who are undergoing emergency intubation in the ED and ICU

Treatment:

Diagnostic Test: Waveform capnography

Diagnostic Test: Colorimetric carbon dioxide (CO2) detection