Weaning is Winning? (WeWin Study)

The Hospital for Sick Children

Status: Enrolling

Conditions: Intestinal Failure; Parenteral Nutrition

Treatments: Other: Weaning off Parenteral Nutrition

Study type: Observational

Funder types: Other

Identifiers

NCT06525753

1000080824

Details and patient eligibility

About

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

Full description

Children with IF depend on PN. This is associated with frequent and various complications such as metabolic bone disease, micronutrient deficiencies and abnormal body composition. Due to advancements in care, many patients with IF are able to wean off PN; they are so called PN graduates. It is currently not well known how often complications do occur after weaning off PN, and which patients are at highest risk of developing these complications.

Enrollment: 120 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parenteral Nutrition graduates for at least 1 year, with a history of intestinal failure.
• Age <18 years at time of inclusion.

Exclusion criteria

• No consent provided.

Trial design

120 participants in 2 patient groups

SickKids

Description:

Patients recruited from the Hospital for Sick Children (SickKids), Toronto, Canada

Treatment:

Other: Weaning off Parenteral Nutrition

Erasmus

Description:

Patients recruited from the Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands

Treatment:

Other: Weaning off Parenteral Nutrition