Web-based International Multi-Center Clinical Study for Parkinson's Disease

Seoul National University

Status: Unknown

Conditions: Parkinson Disease

Treatments: Procedure: electrode position

Study type: Interventional

Funder types: Other

Identifiers

NCT01696812

DELAS-201209

DELAS (Other Grant/Funding Number)

Details and patient eligibility

About

The objectives of this study are (1) to compare the clinical outcome in correlation with the electrode positions estimated by web-based image fusion of the preoperative MRI and the postoperative brain CT taken at a stable period after surgery using mutual information technique in the patients with advanced Parkinson's disease (PD) after bilateral STN DBS and (2) to examine whether the documentation of the electrode position by using mutual information technique at a stable period after unilateral or bilateral STN stimulation provides useful information for the postoperative programming.

Enrollment: 136 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Advanced Parkinson Disease patients

Exclusion criteria

• The patients who have experienced any perioperative or postoperative complications
• The patients with severe cognitive impairment, ongoing psychiatric problems, an unsatisfactory general condition for evaluation, or an inability

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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136 participants in 1 patient group

electrode position, STN DBS, Parkinson' disease

Experimental group

Description:

To determine the electrode positions with the relationship of the STN from the fused images of the preoperative MRI and the postoperative CT via web-site.

Treatment:

Procedure: electrode position