Web-Mediated Risk Assessment for Endoscopic Screening of Colorectal Polyps

State Key Laboratory of Cancer Biology

Status: Unknown

Conditions: Colorectal Polyp

Treatments: Diagnostic Test: pre-endoscopic screening risk assessment

Study type: Interventional

Funder types: Other; NETWORK

Identifiers

NCT03750617

xjtu-20170815

Details and patient eligibility

About

Colorectal polyps are risk factors for cancer. Early detection of polyps is critical for colorectal cancer management. However, the diagnosis rate of patients with colorectal polyps is still low. Therefore, we design this study to access whether pre-endoscopic screening risk assessment of genetic and environmental risk factors could improve diagnosis rate of colorectal polyps.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18-65.
2. Signed informed consent

Exclusion criteria

1. Severe back ground disease including malignancy.
2. State after gastric surgery.
3. COPD, CHF, CRF and any disease with respiratory disturbances.
4. Deviation of the nasal septum, lack of venous access at the dorsum of the hand or any other technical problem prevents gastric acid collection or base excess evaluation.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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1,000 participants in 2 patient groups

pre-endoscopic screening risk assessment

Experimental group

Treatment:

Diagnostic Test: pre-endoscopic screening risk assessment

routine screening

No Intervention group