Weight Fluctuation After Breast Cancer Treatment

The Royal Bournemouth Hospital

Status: Completed

Conditions: Breast Cancer; Weight Gain

Treatments: Procedure: Fasting blood sample.

Study type: Observational

Funder types: Other

Identifiers

NCT00991653

08/H0201/35

Details and patient eligibility

About

This study aims to identify and quantify the factors associated with excess weight gain following treatment for breast cancer. It is believed that breast cancer patients gain more than 4% of their weight at diagnosis which is likely accompanied by an increase in body fat and waist circumference. It is further thought that this excess weight and increase in body fat and waist circumference are associated to tumour characteristics, chemotherapy, menopause status at diagnosis and the presence of genes related to obesity. It is also thought that women treated with chemotherapy have higher levels of glucose and insulin.

Enrollment: 250 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Females 18 years of age or older.
• Diagnosed with breast cancer between 1/1/2003 and 31/12/2007.
• Able to understand and willing to sign informed consent.

Exclusion criteria

• Known diagnosis of previous breast/other cancer (other than completely resected non-melanoma skin cancer or successfully treated in situ cancer of the cervix.
• Known diagnosis of inflammatory bowel disease or malabsorption syndrome.
• Known diagnosis of endocrine problems associated with the development of obesity (cushings syndrome, hypo/hyperthyroid, thyroiditis)
• Treatment for psychiatric disorders.

Trial design

250 participants in 1 patient group

Breast cancer

Description:

Diagnosed with breast cancer 1/1/2003 - 31/12/2007.

Treatment:

Procedure: Fasting blood sample.