Weight Loss and Exercise in Physically Limited Obese Elderly Subjects
Status and phase
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Details and patient eligibility
About
The overall purpose of this research is to determine the effect of weight loss and physical training on quality of life, physical function, metabolism, bone strength, body fat and muscle mass.
Full description
Obesity causes serious medical complications and impairs quality of life. Moreover, in elderly persons, obesity can lead to frailty because of decreased strength, joint function, balance and mobility associated with aging. The primary objective of this study is to evaluate the effect of weight loss and physical training on physical function, body composition, metabolism and quality of life in frail, obese elderly men and women. Subjects are randomized to either control or 10% weight loss plus physical training.
Sex
Ages
Volunteers
Inclusion criteria
- Obese (BMI 30 or greater) elderly (age 65 years or older) Frailty
Exclusion criteria
- Major chronic disease or any condition that would interfere with exercise or dietary restriction, in which exercise or dietary restriction are contraindicated, or that would interfere with interpretation of results. Examples include cardiopulmonary disease, unstable disease, severe orthopedic or neuromuscular impairments, dementia, history of malignancy during the past 5 yr, current use of bone acting drugs.
Trial design
Primary purpose
Allocation
Interventional model
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Data sourced from clinicaltrials.gov
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