What is an Important Change in the Short Physical Performance Battery (SPPB)?

Royal Brompton & Harefield NHS Foundation Trust

Status: Completed

Conditions: Lung Diseases; Respiratory Tract Diseases

Treatments: Other: Pulmonary rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT01649193

2012LF001H

Details and patient eligibility

About

The purpose of this study is to determine the important change in the Short Physical Performance Battery (SPPB) when used in patients with lung disease. The SPPB is a simple physical test that measures balance and the functioning of the legs. It has been widely used in healthy elderly populations and predicts hospital admission and the onset of disability. The SPPB has not previously been used in patients with lung disease, and it is not clear what change in this test is considered meaningful and worthwhile by patients or doctors (the minimal clinically important difference: MID). Knowing what the MID for the SPPB will allow researchers and doctors to evaluate the effectiveness of current and new treatments, and to detect improvement or deterioration in the condition of patients.

Enrollment: 400 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients entering pulmonary rehabilitation

Exclusion criteria

• Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause, severe peripheral vascular disease or amputation.
• Any patient whom the chief investigator feels it is unsafe to exercise (e.g. unstable cardiac disease).

Trial design

400 participants in 1 patient group

Chronic Respiratory Disease

Description:

Any patient with a chronic respiratory disease referred for pulmonary rehabilitation

Treatment:

Other: Pulmonary rehabilitation