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What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Status

Completed

Conditions

Invasive Pneumococcal Disease, Recurrent Isolated, 1
Invasive Pneumococcal Disease, Recurrent Isolated, 2
Invasive Pneumococcal Disease, Protection Against
Primary Immunodeficiency

Treatments

Other: Referral to Immunology

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

This is a multicentre prospective audit to determine the incidence of immunodeficiency in children with IPD.

Aims and/or research question of the project

  1. To determine the incidence of primary immunodeficiency in children >2 years who present with IPD
  2. To determine the types of immunodeficiency associated with IPD in children

Enrollment

380 patients

Sex

All

Ages

Under 18 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Children aged 0 to 18 years admitted to one of the six centres with IPD.

Exclusion criteria

  • Children who do not fulfil the age criteria for immunological evaluation at that particular site e.g. aged <2 years at Royal Children's Hospital.
  • Children with a known underlying condition predisposing to IPD i.e. nephrotic syndrome.

Trial design

380 participants in 1 patient group

Children with IPD
Description:
Children with IPD will be referred for immunological evaluation. The protocol for immune work up will be the same but between centres there is variation in the age criteria for referral i.e. \>2 years in some, \>6 months in others.
Treatment:
Other: Referral to Immunology

Trial contacts and locations

6

There are currently no registered sites for this trial.

Timeline

Last updated: Jul 06, 2022

Start date

Jan 31, 2017 • 7 years ago

End date

Jun 30, 2021 • 3 years ago

Today

Jan 21, 2025

Sponsor of this trial

Collaborating Sponsor

R

Royal Children's Hospital

Data sourced from clinicaltrials.gov