When and How to Administer Oxytocin for Active Management of Third Stage of Labour

Etlik Zubeyde Hanim Womens' Health and Teaching Hospital

Status

Completed

Conditions

Postpartum Bleeding

Treatments

Procedure: after delivery of the fetus & when anterior shoulder seen

Drug: intravenous & intramuscular oxytocin

Study type

Interventional

Funder types

Other

Identifiers

NCT01954186

EtlikWHTH

Details and patient eligibility

About

To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).

Full description

Our objective is to determine the most efficient route and timing of oxytocin administration by measuring the duration of third stage of labour, quantitative blood during the first hour after delivery and comparing haemoglobin and haematocrit changes and the need for additional interventions in patients who had either a spontaneous labour or received labour augmentation with oxytocin.

Enrollment

600 patients

Sex

Female

Volunteers

No Healthy Volunteers

Inclusion criteria

having a singleton pregnancy above 37th gestational week
normal live vaginal delivery with cephalic presentation
being in active labor

Exclusion criteria

Fetal demise
multiple pregnancy
known coagulation disorder
presentation anomalies
placental pathology
liver disease
thrombocytopenia
hypertension or being currently on anticoagulants
having a cesarean section, operative delivery or deep vaginal tear
chorioamnionitis
developing HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) or DIC (disseminated intravascular coagulation) before delivery