Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study

Skidmore College

Status: Completed

Conditions: Overweight; Obesity

Treatments: Dietary Supplement: Whey Protein and Resistance Exericse; Dietary Supplement: Whey Protein; Other: Whey Protein and RISE exercise routine

Study type: Interventional

Funder types: Other

Identifiers

NCT01960335

whey-1001-192

Details and patient eligibility

About

Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy. For example, increased whey protein ingestion with and without exercise training is associated with enhanced weight loss, body composition and subjective hunger in overweight and obese individuals. Our findings suggest that the effects of whey protein ingestion occur independent of a calorie-restricted diet and to a greater extent in individuals following a combined exercise program of resistance exercise, sprint intervals, stretching/yoga/pilates, and aerobic exercise training compared to standard resistance training.

Full description

This study was a 16 week whey protein and exercise training intervention in middle aged overweight/obese adults. Subjects were randomized into 3 groups: Whey protein only consumed as 20 grams per serving three times per day (total 60 grams per day) (WP); Whey protein and resistance exercise training (WP-RT); and Whey protein and combined exercise training (P+RISE). All outcomes, including the primary outcome of visceral fat was measured at baseline (week 0) and post-intervention (week 17) in all study subjects.

Enrollment: 79 patients

Sex: All

Ages: 30 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy, overweight or obese, inactive

Exclusion criteria

• smoker, exercise-trained, recent weight loss, heavy caffeine-consumer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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79 participants in 3 patient groups

Whey Protein Only

Active Comparator group

Description:

Ingestion of whey protein only (20 grams per serving) consumed 3X/day along with ad libitum diet for a total of 60 grams per day. One serving was consumed within 1 hour of waking in the morning; a second serving was consumed mid-afternoon; and a third serving was consumed within 2 hours of going to sleep at night.

Treatment:

Dietary Supplement: Whey Protein

Whey Protein and Resistance Exericse

Experimental group

Description:

Ingestion of whey protein (20 grams per serving) 3X/day: one serving within an hour of waking in morning; a second serving mid-afternoon or within 1 hour immediately following a resistance exercise bout on exercise days; and a third serving within 2 hours of going to bed at night.

Treatment:

Dietary Supplement: Whey Protein and Resistance Exericse

Dietary Supplement: Whey Protein

Whey Protein and RISE exercise routine

Experimental group

Description:

Ingestion of whey protein (20 gram serving) 3X/day: one serving within an hour of waking in the morning; a second serving mid-afternoon or within 1 hour immediately following the RISE exercise bout; and a third serving within 2 hours of going to bed at night.

Treatment:

Dietary Supplement: Whey Protein

Other: Whey Protein and RISE exercise routine