White Cell Ratios as Markers of Delirium and Outcome in Acute Ischemic Stroke. (DELIAS)

Pomeranian Medical University Szczecin

Status: Completed

Conditions: Ischemic Stroke; Delirium

Treatments: Diagnostic Test: Delirium assessment.

Study type: Observational

Funder types: Other

Identifiers

NCT03944694

0012/84/03/19

Details and patient eligibility

About

The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).

Full description

Delirium is an acute brain disorder, potentially reversible, commonly occurring in patients with acute ischemic stroke. The pathomechanism of delirium is related to neuroinflammatory process and oxidative stress. Search for readily available diagnostic marker that will aid clinicians in early identification of delirium is an on-going process. The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).

Enrollment: 1,001 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >18 years)
• acute ischemic stroke

Exclusion criteria

• hematology disorders
• incomplete laboratory testing
• no data regarding follow-up

Trial design

1,001 participants in 2 patient groups

Delirious

Description:

Patients were delirious if CAM-ICU was positive within 24 hours from admission due to acute ischemic stroke.

Treatment:

Diagnostic Test: Delirium assessment.

Non-delirious

Description:

Patients were delirious if CAM-ICU was negative within 24 hours from admission due to acute ischemic stroke.

Treatment:

Diagnostic Test: Delirium assessment.