Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols

Copenhagen University Hospital at Herlev

Status

Completed

Conditions

Intermittent Claudication

Atherosclerosis

Treatments

Procedure: Whole body magnetic resonance angiography (WB-MRA)

Study type

Observational

Funder types

Other

Identifiers

NCT00834548

Herlev WB-MRA 5

Details and patient eligibility

About

To compare to different approaches in whole-body magnetic resonance angiography of patients suffering peripheral arterial disease.

Our hypothesis is that use of a new protocol improves the diagnostic quality of the WB-MRA procedure.

Full description

Patients suffering peripheral arterial disease must undergo imaging procedures before endovascular or surgical procedures.

WB-MRA is an imaging procedure that can visualise the arterial system. WB-MRA can be performed in different manners. On option is to start the scan in the head region and continue down the body to the feet (standard protocol). Another option is to use a hybrid protocol that first examines the head and lower leg followed by examination of the pelvic and upper leg region.

A comparison between the standard and hybrid protocols has not been performed in a 3T high magnetic field system, therefore we will perform such a study.

Enrollment

26 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Symptomatic lower extremity ischemia (claudication, ischemic wounds)
Referred to digital subtraction angiography (DSA)

Exclusion criteria

Renal insufficiency (GFR < 30 ml/min)
Contra-indications for MRI-examination (claustrophobia, metal-implants, pacemaker)
Dementia
Pregnancy/lactation
Allergy to gadolinium based MRI contrast agents
Acute disease