Whole Body Vibration Versus Aerobic Training on Interleukin 6 and Endurance After Renal Transplantation

Cairo University (CU)

Status: Completed

Conditions: Whole Body Vibration; Endurance; Interleukin 6; Aerobic Training; Renal Transplantation

Treatments: Device: whole body vibration; Device: stationary bicycle

Study type: Interventional

Funder types: Other

Identifiers

NCT07333105

Zeinab-phd

Details and patient eligibility

About

This study aimed to compare the effect of whole body vibration versus aerobic training on interleukin 6 and endurance after renal transplantation in patients after renal transplantation.

Full description

Even after a successful renal transplantation, the renal transplant recipients (RTRs) keeps on suffering the consequences of the uremic sickness such as increased cardiovascular risk, elevated level of inflammatory cytokines (IL6), decrease work capacity and quality of life. Since biological and psychological problems are not completely solved by pharmacological treatment, physical training is able both, to improve graft function, work capacity and quality of life, and to reduce cardiovascular risk Therefore, this research aims to investigate effect of the whole-body vibration versus stationary bicycle as modes of aerobic exercises on interleukin 6 in patients and the 6-minutes walk test after renal transplantation, which may reduce the risks of cardiovascular disease, produce improvement of the biology of transplantation, increase of energetic metabolism, and allows for a better quality of life in these subtypes of patients.

Enrollment: 60 patients

Sex: All

Ages: 30 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of both sexes undergone renal transplantation.
• Their age will range from 30-45 years old.
• All patients will have the same medical and nursing care.
• All the patients will receive a good explanation of treatment and measurement device.
• They will be free from any genitourinary infections.
• They will be neurologically free.

Exclusion criteria

• Uncooperative patients
• Instability of patient's medical condition.
• Association of another medical problem as heart disease and respiratory problems.
• Diabetic patients.
• Patients who have history of medical chronic relevant diseases.
• Patients who have acute or chronic hepatitis.
• Patients have pacemaker.
• Patients who have genitourinary infections.
• Previous history of epilepsy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

whole body vibration

Experimental group

Description:

In this group of the study, thirty renal transplant recipients' patients will receive the whole-body vibration for, 20 minutes 3 times per week for 12 weeks after one month post renal transplantation

Treatment:

Device: whole body vibration

stationary bicycle

Experimental group

Description:

In this group, thirty renal transplant recipients' patients will receive aerobic exercise on stationary bicycle for 20 minutes 3 times per week for 12 weeks after one month post renal transplantation

Treatment:

Device: stationary bicycle