Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea

Mayo Clinic

Status

Enrolling

Conditions

Daytime Sleepiness

Obstructive Sleep Apnea

Treatments

Behavioral: Whole Food Plant-Based Diet

Study type

Interventional

Funder types

Other

Identifiers

NCT06395181

23-011675

Details and patient eligibility

About

This research aims to develop a better understanding and clinical knowledge of the effects of a plant based diet on severity and daytime sleepiness in Obstructive Sleep Apnea.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Daytime sleepiness with ESS score ≥ 5.
Patient's prior sleep study with AHI between ≥ 10 and ≤ 45 (4% scoring criterion).
On treatment for OSA, failed or not willing to use all other OSA treatment options
Has access to a weight scale at home or able to come into the Sleep Clinic to be weighed after the 8-week plant-based diet period.

Exclusion criteria

Pregnancy or lactation.
Current use of a vegan diet.
BMI ≤ 22.
Complex, central sleep apnea.
Pre-existing significant degree of cardio-pulmonary disease-heart failure with reduced EF of 35 or lower, unstable arrythmia, severe degree of pulmonary hypertension, severe degree of obstructive or restrictive lung disease including COPD and Interstitial lung disease.
On weight loss medications or starting new exercise regimen during the 8-week plant-based diet period.