Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?

Norwegian University of Science and Technology

Status: Completed

Conditions: Needlestick Injuries

Treatments: Procedure: lidocaine injection; Procedure: Lidocaine injection with bicarbonate

Study type: Interventional

Funder types: Other

Identifiers

NCT02107716

2013/2297A

Details and patient eligibility

About

This study will investigate the influence of adjusting the pH of lidocaine on pain during subcutaneous injection. Each participant will receive two injections on the abdomen with different pH. After each injection, the subject will be asked to evaluate the pain on a Visual analog scale (0-100 mm). It is anticipated that the pain decreases with increasing pH. The aim of the study is to find a simple method for pain reduction that can be used in clinical practice.

Enrollment: 32 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: fyll inn

• Age 18-65 years

Exclusion Criteria:

• Kidney, heart or liver disease
• Eczema or psoriasis on injection site
• Neuropathy
• Regular use of painkillers
• Hypersensitivity of Lidocaine
• Pregnancy
• Diabetes

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Double Blind

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32 participants in 1 patient group

Bicarbonate

Experimental group

Description:

Each participant will receive two lidocaine injections on the abdomen with different pH

Treatment:

Procedure: lidocaine injection

Procedure: Lidocaine injection with bicarbonate