Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery?

Wills Eye

Status and phase

Completed

Phase 3

Phase 2

Conditions

Glaucoma

Treatments

Drug: Triesence

Drug: balanced salt solution BSS

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT00853905

07-827

Details and patient eligibility

About

The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure.

Full description

Determine the efficacy and safety of intracameral Triesence in patients who undergo trabeculectomy, tube shunt, or combined cataract extraction, intra-ocular lens implantation and trabeculectomy with or without adjunctive mitomycin-C.

Enrollment

77 patients

Sex

All

Ages

21+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

glaucoma patients requiring surgery (Trabeculectomy or Express Shunt; Trabeculectomy plus Phacoemulsification and Interocular Lens Implant; Baerveldt Tube; Ahmed Tube; Molteno Tube)
primary open angle glaucoma
primary angle-closure glaucoma
pseudoexfoliation glaucoma
pigmentary glaucoma
traumatic glaucoma
neovascular glaucoma

Exclusion criteria

patients that are pregnant, nursing, or not using adequate contraception
any other eye surgery except cataract surgery
an infection, inflammation, or any abnormality preventing measurement of eye pressure
enrolled in another investigational study