Women At Risk: The High Risk Breast Cancer Program (WAR)

New York Presbyterian Hospital

Status: Unknown

Conditions: Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01034891

AAAA4649

Details and patient eligibility

About

The purpose of this study is to increase understanding of women who are at high risk for developing breast cancer. Data from this group will be collected and entered into a registry. This registry serves as a clinical database to support research in prevention, early detection and treatment of breast cancer.

Full description

This is a longitudinal cohort study that collects data of eligible women at risk for developing breast cancer. Patient information will be entered into a secured computerized database that is used for research on the prevention, early detection and treatment of breast cancer.

Enrollment: 2,000 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• one or more first-degree relatives (mother, daughter, or sister) with pre-menopausal breast cancer
• two or more first-degree relatives with post-menopausal breast cancer
• tested positive for a BRCA1 or BRCA2 mutation
• a history of biopsy-proven atypical ductal hyperplasia or atypical lobular hyperplasia
• a history of biopsy-proven lobular neoplasia (lobular carcinoma in situ)

Exclusion criteria

• DCIS (ductal carcinoma in situ)
• previous diagnosis of breast cancer