Women With Migraine With Aura Neuroimaging Study (WOMAN)

Odense University Hospital

Status: Completed

Conditions: Migraine With Aura

Study type: Observational

Funder types: Other

Identifiers

NCT02047695

S-20100126

Details and patient eligibility

About

The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain

Enrollment: 345 patients

Sex: Female

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• female
• case (migraine with aura), co-twin to case, or control (migraine-free)
• residency in Denmark
• no severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders

Exclusion criteria

• male
• residency outside Denmark
• registered in Civil Registry as not to be contacted by researchers
• severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
• mobile metal parts or other contraindication for MRI
• weight of 130+ kilograms
• pregnancy
• subjects that wished not to be informed about abnormal findings on MRI
• chronic tension-type headache, medication overuse headache, or cluster headache (diagnosed through physician interview)
• frequent tension-type headache (control group only, self-reported or diagnosed through physician interview)

Trial design

345 participants in 1 patient group

Migraine with aura

Description:

Participants with migraine with aura (cases), their co-twins, and unrelated migraine-free twins (controls)