Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

Gulhane School of Medicine

Status: Completed

Conditions: Polycystic Ovary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01382576

1491-81-11/1539-1563

Chitotriosidase activity (Other Grant/Funding Number)

Details and patient eligibility

About

In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

Full description

ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Enrollment: 78 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Absence of significant abnormalities on physical examination except hirsutism
• no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
• normal thyroid function and prolactin level
• absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease

Exclusion criteria

• Pregnant
• ovarian tumors
• congenital adrenal hyperplasia or BMI greater than 30 kg/m2

Trial design

78 participants in 2 patient groups

PCOS patients

PCOS patients and healthy controls

Description:

There are two groups in this study. One group is PCOS patients and other group is healthy controls.