Women's Health Initiative Strong and Healthy Study (WHISH)

Fred Hutchinson Cancer Center (FHCC)

Status: Completed

Conditions: Mortality; Venous Thromboembolic Event; Physical Function; Peripheral Artery Disease; Stroke; Myocardial Infarction; Coronary Revascularization; Mobility and Independence; Depressive Symptoms; Hip Fractures; Cardiovascular Mortality; Clinical (Non-hip) Fractures; Falls; Sleep

Treatments: Behavioral: Physical Activity

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02425345

4R33HL151885-02

RG1001184 (Other Identifier)

1U01HL122273-01A1 (U.S. NIH Grant/Contract)

1U01HL122280-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise & Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.

Enrollment: 49,331 patients

Sex: Female

Ages: 66 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Currently enrolled in the Women's Health Initiative (WHI) Extension Study
• Known to be alive
• Cardiovascular outcomes will be available (enrolled in the WHI Medical Records Cohort or linked to Medicare Data)

Exclusion criteria

• Inability to walk
• Dementia
• Residing in a nursing home

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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49,331 participants in 2 patient groups

Physical Activity Intervention

Experimental group

Description:

The Physical Activity Intervention Group will receive guidance on being physically active, including aerobics, flexibility, balance, strength, and decreased sedentary time. The primary resource is the National Institute of Aging Go4Life exercise and physical activity materials. The materials are based on the United States national guidelines for physical activity for older adults

Treatment:

Behavioral: Physical Activity

Usual Activity Control

No Intervention group

Description:

Usual activity