Working Memory Training for Chronic Neuropathic and Fibromyalgia Pain (NEPA)
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Treatments
Details and patient eligibility
About
The goal of this project is to investigate and improve executive control function in two distinct pain conditions, namely neuropathic pain and fibromyalgia (FM). It is hypothesized that there is a significant difference in the executive control function of patients with neuropathic pain and FM pain. It is also hypothesized that all participants with poor executive control functioning will report significant improvements in pain intensity, functioning and cognitive complaints following cognitive training. The study tests and influence the working memory concepts of inhibition, updating and flexibility through an experimental, cross-over treatment design.
To perform the experiment, we will recruit 160 participants (80 with neuropathic pain and 80 with FM) from the Departments of pain management and research at St Olav's University Hospital and Oslo University Hospital (OUS). The proposed design will be able to determine whether or not executive control, processing speed and memory function differs in two distinct populations of pain patients. Moreover, whether impairments are amended by computerized training.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Confirmed diagnosis of fibromyalgia or neuropathic pain
- Confirmed objective cognitive impairments on the CANTAB battery compared to IQ control
Exclusion criteria
- Mania, suicidal ideation and/or active psychosis
- No objective cognitive impairments
- Personality disorders
- Pregnancy
Trial design
Primary purpose
Allocation
Interventional model
Masking
82 participants in 2 patient groups
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Data sourced from clinicaltrials.gov
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