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Working Memory Training in Adults With ADHD

Karolinska Institute logo

Karolinska Institute

Status

Completed

Conditions

Attention Deficit Hyperactivity Disorder

Treatments

Behavioral: Flex working memory training

Study type

Interventional

Funder types

Other

Identifiers

NCT01477125
DAT-KV (Other Identifier)
DAT-NSP (Other Identifier)
X002

Details and patient eligibility

About

The purpose of this study is to evaluate whether computerised working memory training improves cognitive performance, ADHD symptoms, psychosocial functioning and quality of life in adults with ADHD, from psychiatric outpatient clinics (N=100) as well as from a high-security prison facility (N=50).

Full description

The primary aim is to evaluate whether 5 weeks of computerised working memory training improves working memory capacity. Secondary aims are to explore whether improvements in working memory capacity will be transferred to improvements in learning abilities and fluid intelligence. Also, far transfer effects on executive functioning, ADHD symptoms, psychosocial functioning and quality of life will be explored. Finally, it will also be assessed to what extent improvements gained from 5 weeks of working memory training will be maintained 3 and 6 months post-study, respectively.

Enrollment

102 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Confirmed ADHD according to DSM-IV criteria; ADHD combined type, ADHD inattentive type or ADHD UNS, primarily inattentive type.
  • Unmedicated for ADHD during the course of the trial, or being under stable ADHD medication for at least one month at baseline visit and without any planned changes in medication until post-study assessments have taken place.

Exclusion criteria

  • Previous participation in computerised working memory training (completed training).
  • Any psychiatric disorder that in the judgment of the investigator, may interfere with study participation and/or study assessments, also including current substance abuse.
  • Participation in psychological treatment addressing ADHD during the course of the 5-week training period (psychoeducation is accepted).
  • Initiation of psychological treatment for coexistent disorders during the course of the study (treatment already ongoing at baseline visit is accepted if there are no planned changes during the 5-week training period).

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

102 participants in 2 patient groups, including a placebo group

Flex working memory training
Experimental group
Description:
30-40 minutes of working memory training, 5 days a week for 5 weeks
Treatment:
Behavioral: Flex working memory training
Control version of Flex
Placebo Comparator group
Description:
30-40 minutes of training with a control version of Flex, 5 days a week for 5 weeks.
Treatment:
Behavioral: Flex working memory training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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