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Working Memory Training in COPD Patients: the Cogtrain-Trial

Maastricht University Medical Centre (MUMC) logo

Maastricht University Medical Centre (MUMC)

Status

Completed

Conditions

Cognitive Impairment
COPD

Treatments

Other: Working memory training
Behavioral: Standardised healthy lifestyle coaching

Study type

Interventional

Funder types

Other

Identifiers

NCT03073954
NL59883.068.17

Details and patient eligibility

About

General cognitive impairment is highly prevalent in chronic obstructive pulmonary disease (COPD) patients. Domain-specific cognitive impairments include deficits in domains such as cognitive flexibility, verbal memory, working memory, planning, and psychomotor speed; which in general are associated with poor health behaviours, such as infrequent exercising and poor diet. Additional cognitive training may reverse these effects. Recent evidence suggests that working memory training is linked to self-control and, indirectly, to improved lifestyle behaviour including increased physical activity. The investigators hypothesise that enhancing cognitive performance through administering specific working memory training not only improves cognitive function but that it facilitates better adherence to a more active lifestyle and a healthier diet in COPD patients.

Enrollment

75 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • primary diagnosis of COPD based on the Global Initiative for Chronic obstructive Lung Disease (GOLD) guidelines
  • Patients also need to provide written informed consent
  • Be motivated as evaluated by the self-determination questionnaire

Exclusion criteria

  • Disease and or disability limiting the ability to undergo a neuropsychological testing battery and/or to follow a working memory training (e.g., blindness)
  • Neurological disorders (e.g., Alzheimer's Disease or cerebrovascular disease)
  • Insufficient mastery of the Dutch language
  • Individuals who during the study period are or will be participating in a PR programme

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

75 participants in 2 patient groups

Working memory training
Active Comparator group
Description:
Working memory training that increases with difficulty if participants answer two subsequent questions correctly, and standardised healthy lifestyle coaching.
Treatment:
Behavioral: Standardised healthy lifestyle coaching
Other: Working memory training
Sham working memory training
Sham Comparator group
Description:
Working memory training that does not increase in difficulty, and standardised healthy lifestyle coaching.
Treatment:
Behavioral: Standardised healthy lifestyle coaching
Other: Working memory training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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