Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

Tang-Du Hospital

Status: Completed

Conditions: Wound Healing Disturbance of; Disorder of Skin Donor Site; Skin Graft Disorder

Treatments: Procedure: regrafted with thin split-thickness skin graft; Procedure: covered with the occlusive hydrocellular dressing; Procedure: covered with paraffin gauze

Study type: Observational

Funder types: Other

Identifiers

NCT01974583

TDLL-2030130

Details and patient eligibility

About

Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Full description

Background：Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

Enrollment: 192 patients

Sex: All

Ages: 5 to 56 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who continuously received an STSG from January 2002 to December 2010 in Department of Burn and Plastic Surgery, Tangdu Hospital, Fourth Military Medical University

Exclusion criteria

• The patients who were significant psychiatric, hypersensitive to silver, and not be followed up were excluded

Trial design

192 participants in 3 patient groups

the treatment group A

Description:

The people in treatment group were regrafted with thin split-thickness skin graft

Treatment:

Procedure: regrafted with thin split-thickness skin graft

the control group B

Description:

The group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith \& Nephew)

Treatment:

Procedure: covered with the occlusive hydrocellular dressing

the control group C

Description:

Group C were covered with paraffin gauze

Treatment:

Procedure: covered with paraffin gauze