Wound Infiltration With Ketorolac Versus Lidocaine for Postoperative Analgesia After Total Abdominal Hysterectomy

Ain Shams University

Status and phase: Unknown; Phase 4

Conditions: Anesthesia

Treatments: Procedure: Wound infiltration; Drug: Lidocaine Hydrochloride; Drug: Ketorolac tromethamine

Study type: Interventional

Funder types: Other

Identifiers

NCT03394001

FMASU R47/2017

Details and patient eligibility

About

The main goal of this study is to compare wound infiltration with ketorolac versus lidocaine for postoperative analgesia in total abdominal hystrectomy (TAH) operation.

Enrollment: 80 patients

Sex: Female

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA physical status I and II
• Planned for elective TAH with a Pfannenstiel incision

Exclusion criteria

Patients with the following criteria will be excluded from the study;

• ASA physical status more than II
• Body mass index (BMI)>35 kg/m2
• Previous abdominal surgeries
• Malignancy
• Individuals with chronic pain
• A history of severe systemic disease
• A pre-existing neurological or psychiatric illness
• Known to be addict on alcohol or drugs
• Known allergy to the study drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups

Lidocaine Hydrochloride

Active Comparator group

Description:

Wound infiltration with Lidocaine

Treatment:

Procedure: Wound infiltration

Drug: Lidocaine Hydrochloride

Ketorolac tromethamine

Active Comparator group

Description:

Wound infiltration with Ketorolac

Treatment:

Drug: Ketorolac tromethamine

Procedure: Wound infiltration