Wrinkle Injection With Autologous Platelet Rich Plasma Study (WIPES)

Novena Medical Center

Status and phase

Withdrawn

Phase 1

Conditions

Wrinkles

Treatments

Device: MyCells® (injection of platelet rich plasma)

Study type

Interventional

Funder types

NETWORK

Identifiers

NCT01078493

CTC1000031

Details and patient eligibility

About

Wrinkles result from imperfect repair of the dermal layer resulting in loss of collagen commonly due to ageing, smoking and sun exposure. Platelet rich plasma (PRP) contains a host of growth factors, which have been used in other clinical trials for various medical conditions such as tendonitis, and also in surgery such as the surgical repair of facial defects. Results from these clinical trials suggest that PRP helps in collagen formation and organisation to promote healing of tissues. This study attempts to document the clinical effects of intradermal injection of PRP on wrinkles.

Full description

10 selected participants will have 10 ml of blood removed for platelet extraction with MyCells®. The resulting Platelet rich plasma will be injected intradermally into the facial wrinkles.

Sex

All

Ages

21+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Adults more than 21 years of age
Dis-satisfied or anxious about facial wrinkles (total wrinkle length more than 1cm)

Exclusion criteria

Pregnant women.
Psychiatric patients.
Known bleeding disorders such as platelet dysfunction syndrome, thrombocytopenia, hypofibrinogenemia
Anticoagulants(eg.aspirin, warfarin)
Had other wrinkle therapy for less than a month.(laser, peels, injections)
Had facelift surgery for less than a year.
Diseased states such as organ failure, severe anaemia, cancer, acute/chronic infections.
Involved in personal litigation against an aesthetic service provider