Wroclaw Out-Of-Hospital Cardiac Arrest Registry (WOHCA)

Wroclaw Medical University

Status: Enrolling

Conditions: Out-Of-Hospital Cardiac Arrest

Treatments: Other: ECMO assisted CPR in out-of-hospital cardiac arrest

Study type: Observational

Funder types: Other

Identifiers

NCT05132387

327/2021

Details and patient eligibility

About

The purpose of this study is to assess the efficacy of institutionalized care program of patients with out-of-hospital cardiac arrest.

Full description

Patients with out-of-hospital cardiac arrest included in the program will be treated with extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation (CPR) with additional invasive procedures including coronary/pulmonary angiography and intervention. This type of treatment was not provided in institutionalized fashion in Wroclaw, Poland. Implementation of this program should improve survival in out-of-hospital cardiac arrest patients, which currently is less than 10%.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age < 60 years
• witnessed sudden cardiac arrest with immediate CPR
• supposed cardiac cause of the event
• ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) at first medical contact with 3 unsuccessful defibrillations (no ROSC)
• CPR conducted with Lund University Cardiopulmonary Assist System (LUCAS™)
• Estimated transfer time from the scene to the Emergency Department < 30 minutes.
• End tidal carbon dioxide (ETCO2) > 10 mmHg

Exclusion criteria

• Total presumed time from 112 call to ECMO implantation longer than 60 minutes
• Age < 18 years old or > 60 years old;
• Non-shockable initial rhythm
• Unavailability of the automated CPR device
• Unavailability of the catheterisation laboratory
• Severe concomitant illness with decreased life expectancy
• Severe body injury
• Severe active bleeding
• Drowning
• Terminal cancer

Trial design

50 participants in 1 patient group

Out-of-hospital cardiac arrest

Description:

Patients with out-of-hospital cardiac arrest which occured in the predefined area of the city of Wroclaw.

Treatment:

Other: ECMO assisted CPR in out-of-hospital cardiac arrest