Xanthohumol and Viral Infections (XL)

University of Vienna

Status: Enrolling

Conditions: Infection Viral

Treatments: Dietary Supplement: Xanthohumol; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06286657

UVienna23a

Details and patient eligibility

About

The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.

Full description

In this placebo-controlled study, blood is taken on the first day of the study, followed by a 90-day intervention with xanthohumol or a placebo, which is taken twice daily. Blood samples will be taken on day 0, day 45 and day 90. Should the study participants develop a respiratory infection during the study, they will be asked to perform a self-test.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy
• BMI >18 kg/m² or < 28kg/m²

Exclusion criteria

• food intolerances
• food allergies
• chronic inflammatory diseases
• metabolic diseases
• viral or bacterial infections within the last 3 weeks of inclusion
• intake of immunosuppressive medication
• severe acute respiratory syndrome coronavirus type 2-infection in the last 4 months
• influenza infection in the "current" flu season

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

100 participants in 2 patient groups

Intervention

Experimental group

Description:

Participants consume twice per day a study drink which contains 0,75 mg soluble Xanthohumol for 90 days

Treatment:

Dietary Supplement: Xanthohumol

Placebo

Experimental group

Description:

Participants consume twice per day a study drink which contains 0 mg soluble Xanthohumol for 90 days

Treatment:

Dietary Supplement: Placebo