Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

Rudolf Foundation Clinic

Status: Unknown

Conditions: Age-Related Macular Degeneration

Treatments: Procedure: drawing blood

Study type: Interventional

Funder types: Other

Identifiers

NCT00533754

EK 06-076-VK

Details and patient eligibility

About

The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.

Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• man and women over 18 years old
• Filled out informed consentBereitschaft zur Teilnahme
• Diagnosis of non-exudative/ exudative age related macular dgeneneration

Exclusion criteria

• inherited retinal diseases
• other aquired retinal/ macular
• missing informed consent

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind