Yan Nian Jiu Zhuan Fa Improve Chronic Fatigue Syndromes (YNJZFCFS)

Shanghai University of Traditional Chinese Medicine

Status: Unknown

Conditions: Chronic Fatigue Syndromes

Treatments: Behavioral: Yan Nian Jiu Zhuan Fa

Study type: Interventional

Funder types: Other

Identifiers

NCT03496961

81774443

Details and patient eligibility

About

This study is to disclose the mechanism of characteristic Tao yin exercises regulate Chronic Fatigue Syndromes based on Brain-Gut Axis.Explore the clinical manifestation of Chronic Fatigue Syndromes, changes of neurotransmitter and central brain function. Then provide some new methods of treating Chronic Fatigue Syndromes.

Full description

This research will be conducted in Shanghai University of Traditional Chinese Medicine.Then the clinical efficacy of Yan Nian Jiu Zhuan Fa on Chronic Fatigue Syndrome will be observed by examining gastrointestinal function, affecting the content of substances in plasma and analysing the central nerve response mechanism.

Enrollment: 135 estimated patients

Sex: All

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

The occurrence of four or more of the following symptoms:

• Subjective memory impairment
• Tender lymph nodes
• Muscle pain
• Joint pain
• Headache
• Unrefreshing sleep
• Post-exertion malaise lasting for more than 24 hours

Exclusion criteria

• Active, unresolved, or suspected medical disease
• Psychotic, melancholic or bipolar depression (but not uncomplicated major depression)
• Psychotic disorders
• Dementia
• Anorexia or bulimia nervosa
• Alcohol or other substance misuse
• Severe obesity.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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135 participants in 3 patient groups, including a placebo group

Yan Nian Jiu Zhuan Fa

Experimental group

Description:

The kneading process will be done under the therapist guidance for 30 minutes with an average pressure of 5 Newton each time for 3 times every day.

Treatment:

Behavioral: Yan Nian Jiu Zhuan Fa

cognitive psychology education

Placebo Comparator group

Description:

Psychological counseling and behavioral cognition education are conducted once a week and the rest 6 times online or by phone.

Treatment:

Behavioral: Yan Nian Jiu Zhuan Fa

blank control

No Intervention group

Description:

this group will have no therapeutic exercises or cognitive education when other two groups receive therapy.