Yoga and Aerobic Exercise Effects on Cognition

University of Illinois at Urbana-Champaign

Status: Completed

Conditions: Stress, Psychological

Treatments: Behavioral: Seated rest; Behavioral: Aerobic exercise; Behavioral: Sun salutations

Study type: Interventional

Funder types: Other

Identifiers

NCT04077645

20067

Details and patient eligibility

About

The purpose of this acute randomized control study is to assess the feasibility of a low-to-moderate intensity Yoga intervention (i.e. sun salutations), and examine its effect on cognitive functioning, compared to engaging in aerobic activity or seated rest. Participants will include individuals who are currently experiencing symptoms of psychosocial stress or general anxiety.

Full description

Eligible participants will be randomized to one of three groups: 1. Sun salutations (Yoga), 2. Aerobic exercise (walking on a treadmill), 3. Seated rest (watching educational videos). Each activity will be 30 minutes in duration. Immediately before and after the 30 minute intervention, participants will undergo psychosocial and cognitive assessments. Prior to the intervention, participant's physical activity will be tracked for one week, via a consumer grade accelerometer.

Baseline and post-intervention testing will include a cognitive battery, psychosocial questionnaires, flexibility testing and physiological measures.

Enrollment: 71 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Anyone between the ages of 18-45 years

• Anyone with a score of 3 or higher on the Generalized Anxiety Disorder symptom checklist of the Diagnostic and Statistical Manual 5. That is, anyone meeting 3 or more symptoms, on more days of the week than not, for the past 6 months:

  1. Restlessness, feeling keyed up or on edge. 2. Being easily fatigued. 3. Difficulty concentrating or mind going blank. 4. Irritability. 5. Muscle tension. 6. Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep).

• Ability to exercise at moderate to vigorous activity levels (defined as 50%-75% of the adjusted age-predicted maximum heart rate)

• Access to a smartphone and willingness to allow research staff to install a mobile activity tracker application (and space to allow for installation)

• Willingness to be randomized into one of three groups

Exclusion criteria

• Anyone who is physically active (≥30 minutes, 2 or more times/week, for the last 3 months) and/or a regular practitioner of Yoga or mind-body activities (≥30 minutes, 2 or more times/week, for the last 3 months).
• Anyone with serious chronic medical conditions that would preclude them from participating without a physician present, or anyone with a risk of seizure, or anyone having psychiatric and/or neurological disorders.
• Anyone who does not consent to wearing the Fitbit, or does not have a smartphone that allows us to download an app on their phone.
• Pregnant women.
• Anyone incapable of performing the following movements at a moderate intensity- sitting, standing, kicking, pulling, pushing, bending one's elbows, bending the body forward, bending one's knees, lying down and getting up.
• Anyone with blood pressure of 200/105 or more, and anyone who scores 1 or more on the Physical Activity Readiness Questionnaire
• Anyone refusing or unwilling to be randomized into either of the conditions.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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71 participants in 3 patient groups

Sun salutations

Experimental group

Description:

Sun salutations, breathing exercises, and relaxation, at a low to moderate intensity, for 30 minutes.

Treatment:

Behavioral: Sun salutations

Aerobic exercise

Active Comparator group

Description:

Walking on a treadmill at low to moderate intensity for 30 minutes.

Treatment:

Behavioral: Aerobic exercise

Seated rest (attentional control)

Other group

Description:

Watching educational videos for 30 minutes.

Treatment:

Behavioral: Seated rest