Yoga in Patients With Fibrosing Interstitial Lung Diseases

Heidelberg University

Status: Completed

Conditions: Fibrosing Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis

Treatments: Other: 12 week yoga class

Study type: Interventional

Funder types: Other

Identifiers

NCT03979703

Yoga-Study

Details and patient eligibility

About

Fibrosing interstitial lung diseases are characterized by loss of lung function, which leads to a decrease in quality of life and physical capacity. Several studies have shown an increase in quality of life and physical capacity after increasing physical activity in patients. There is evicence that yoga has a positive influence in patients with chronic obstructive pulmonary diseases, but so far, studies examining the effect of yoga in patients with fibrosing interstitial lung diseases are missing.

Study aims are to determine the feasibilty of this study, and to determine the effects of yoga to patients' quality of life and physical capacity.

Twenty patients with a fibrosing interstitial lung disease will be recruited and randomly assigned to the intervention or control group. Several questionnaires regarding quality of life will be conducted. Furthermore, the 6 minutes walking test, a lung function test and a biomarker analysis will be conducted at baseline and follow-up. The intervention group will participate in a 12 week yoga class, whereas the controll group will not participate. Yoga classes will be offered to the control group after the study.

In addition, focus group interviews will be conducted at baseline and follow-up with the intervention group.

Full description

Patients with a fibrosing interstitial lung disease will be recruited. In total 20 patients will be recruited, 10 for the intervention group and 10 for the control group.

The Intervention group will participate in a 12 week yoga class with classes twice a week for about 1 hour. The control group will not participate in a yoga class.

At baseline all patients will conduct a 6 minutes walking test, a lung function test, several surveys to measure health related quaility of life (King's Brief Interstitial Lung Disease Questionnaire (K-BILD), Hospital Anxiety and Depression Scale (HADS), Interstitial Lung Disease Anxiety questionnaire), and some blood will be drawn for biomarker analysis.

Furthermore, participants in the Intervention group will participate in two focus group interviews, one at baseline and the second one at 12 week follow-up.

Enrollment: 17 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ability to understand study and study procedure
• diagnosis of fibrosing interstitial lung disease
• Age: > 18 years
• Ability to consent

Exclusion criteria

• Forced Vital Capacity < 50%
• Oxygen therapy
• diagnosis of pulmonary hypertension
• participant does not understand the study
• pulmonary infection within the last 4 weeks
• acute exacerbation within the last 4 weeks
• other respiratory decline within the last 4 weeks
• co-morbidities which make yoga training impossible

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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17 participants in 2 patient groups

Intervention group

Experimental group

Description:

Intervention will be a 12 week yoga class

Treatment:

Other: 12 week yoga class

Control group

No Intervention group

Description:

Control group will not participate in the 12 week yoga class but will participate in Surveys, 6 minute walking test, lung function test, and biomarker analysis. Furthermore, they will be offered a yoga class after the study.