Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke

The Florey Institute of Neuroscience and Mental Health

Status: Not yet enrolling

Conditions: Young Adults; Stroke; Sequelae; Stroke; Stroke Patients

Treatments: Other: No Intervention: Observational Cohort

Study type: Observational

Funder types: Other

Identifiers

NCT07019493

RARUR000042 (Other Grant/Funding Number)

Protocol One YSSDP

Details and patient eligibility

About

We are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke. Our goal is to test how practical it is to carry out a detailed health assessment process-called "deep phenotyping"-with this group.

This process involves collecting a wide range of information and samples from stroke survivors to better understand each participant's condition. We'll look at how well this approach works in practice, including how easy it is to use, whether it's done consistently, and how acceptable it is to participants.

At the same time, we'll also explore how different factors-such as biological markers (biomarkers), age, sex, type of stroke, lifestyle, and environment-might be related to stroke recovery. This pilot study will help us prepare for larger studies in the future.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Between 18 and 55 years.
2. Within one month of acute stroke confirmed with standard of care brain imaging or clinical diagnosis

Exclusion criteria

1. Severe, intercurrent or progressive illness likely to EITHER

   1. Have a prognosis for survival under 24 months; OR
   2. In the opinion of the investigator will mask the importance to the individual participant data (e.g. severe MS, dementia, etc)

2. Major psychiatric condition requiring medical intervention

Trial design

100 participants in 1 patient group

Young adult stroke survivors (age 18 to 55 inclusive)

Treatment:

Other: No Intervention: Observational Cohort