Youth Nominated Support Team (YST)

University of California Irvine (UCI)

Status: Enrolling

Conditions: Family Members; Psychosis; Health Care Utilization; Suicide

Treatments: Behavioral: Youth-Nominated Support Teams for CHR

Study type: Interventional

Funder types: Other

Identifiers

NCT05558332

2136

Details and patient eligibility

About

This study aims to adapt the current Youth-Nominated Support Team (YST) manual used to treat suicide risk for people at clinical high risk for psychosis.

Full description

Psychotic disorders are characterized by high rates of suicidal ideation and behavior, and the risk for suicide appears to be greatest during the earliest stages of psychosis. A recent meta-analysis showed that the majority of youth at clinical high-risk (CHR) for psychosis experience suicidal ideation, and that approximately one in five make at least one suicide attempt. There are, however, no suicide prevention interventions specifically tailored to the needs of transition-aged youth at CHR, and no current best practice guidelines for how to respond to suicide risk in this population. The Youth-Nominated Support Team (YST) intervention has recently been shown to reduce mortality among adolescents and is potentially highly adaptable within the context of existing CHR services. YST is intended as an adjunctive treatment and is primarily delivered towards support persons rather than the youth themselves, and therefore would not interfere or overlap with the already extensive direct services provided in CHR treatment settings. The proposed project intends to adapt the YST intervention for CHR populations. Specifically, the investigators aim to: (1) adapt YST for CHR based on stakeholder input (i.e., clients, family/friends, clinicians) and to develop a new treatment manual and submit an additional IRB to cover the next two aims -- (2) to implement YST in a single CHR clinic and to revise the intervention based on input from clients, providers, and support person and (3) conduct a pilot randomized clinical trial at four SAMHSA funded CHR sites to test the efficacy of the adapted YST intervention and to identify underlying mechanisms of change. The investigators hypothesize that the revised intervention will be superior to existing practice for the reduction of suicidal ideation and behavior.

Enrollment: 70 estimated patients

Sex: All

Ages: 12 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A person with suicidal ideation in the past 3 months or suicidal attempt in the past year
• A person who is receiving or has received treatment for psychosis risk symptoms
• Between the ages of 12-25

Exclusion criteria

• Cannot have participated in the first 2 phases of the study (focus groups and adaption of the YST-CHR manual)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

YST-CHR Group

Experimental group

Description:

This group will recieve the new adapted YST treatment (YST-CHR). Clinicians will administer this treatment. Neither group will be blind.

Treatment:

Behavioral: Youth-Nominated Support Teams for CHR

Treatment as usual

No Intervention group

Description:

This group will receive their usual therapy/treatment as usual.