Zambia Healthy Choices Project for Emerging Adults Living With HIV

University of Massachusetts, Worcester

Status: Active, not recruiting

Conditions: Pre-Exposure Prophylaxis

Treatments: Behavioral: Motivational Text Messaging (MTM); Behavioral: Mobile Healthy Choices (mHC); Behavioral: Standard ART Counseling

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06415357

STUDY00001496

1R34DA059935 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This project will develop and implement a multi-component intervention using mobile health technology to improve HIV self-management and reduce substance use. Specifically, the investigators will adapt Healthy Choices (HC) to develop mobile HC (mHC) and develop Motivational text messaging (MTM) for Zambian emerging adults living with HIV.

Enrollment: 164 patients

Sex: All

Ages: 18 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Zambian emerging adults living with HIV

Inclusion Criteria:

• Aged between 18 and 24 years
• Report visual analogue scale showing <80% medication adherence in the last month AND problematic/risky alcohol use in the last month
• Speak English, Nyanja, or Bemba

Exclusion Criteria:

• Have a serious cognitive or psychiatric problem that would compromise ability to provide informed consent
• currently enrolled in another HIV intervention study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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164 participants in 4 patient groups

Standard ART counseling, mHC, and MTM

Experimental group

Description:

Participants in this arm will receive standard ART counseling, followed by two mHealth interventions (mHC and MTM) to improve PrEP uptake and adherence.

Treatment:

Behavioral: Standard ART Counseling

Behavioral: Mobile Healthy Choices (mHC)

Behavioral: Motivational Text Messaging (MTM)

Standard ART counseling and mHC

Experimental group

Description:

Participants in this arm will receive standard ART counseling, followed by one mHealth intervention (mHC) to improve PrEP uptake and adherence.

Treatment:

Behavioral: Standard ART Counseling

Behavioral: Mobile Healthy Choices (mHC)

Standard ART counseling and MTM

Experimental group

Description:

Participants in this arm will receive standard ART counseling, followed by one mHealth intervention (MTM) to improve PrEP uptake and adherence.

Treatment:

Behavioral: Standard ART Counseling

Behavioral: Motivational Text Messaging (MTM)

Standard ART counseling

Active Comparator group

Description:

Participants in this arm will receive standard ART counseling.

Treatment:

Behavioral: Standard ART Counseling