Zinc Absorption From Zinc Citrate, Zinc Gluconate and Zinc Oxide

Prof. Michael B. Zimmermann

Status

Completed

Conditions

Healthy

Treatments

Dietary Supplement: Zinc oxide

Dietary Supplement: zinc citrate

Dietary Supplement: Zinc Gluconate

Study type

Interventional

Funder types

Other

Identifiers

NCT01576627

HNL/CTC11-12

Details and patient eligibility

About

The goal of this trial is to evaluate zinc citrate, a zinc compound with promising sensory properties and a high zinc content, as an alternative zinc compound to be used for supplementation or food fortification. The bioavailability of zinc citrate given as a supplement to young Swiss adults will be assessed and compared to the bioavailability of the commonly used zinc compounds zinc gluconate and zinc oxide.

Enrollment

15 patients

Sex

All

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Male or female of 18 to 45 years old
Body Mass Index in the range of 19 to 25
No mineral and vitamin supplements two weeks prior to the study and during the whole duration of the study

Exclusion criteria

Any metabolic, gastrointestinal or chronic disease (according to the subjects own statement)
Long-term medication during the whole study (except for contraceptives)
Vegans
Pregnancy
Lactation
Intention to become pregnant during the course of the study
Lack of safe contraception
Consumption of mineral and vitamin supplements within 2 weeks prior to 1st test supplement administration
Earlier participation in any nutrition study using Zn stable isotopes as well as participation in any other clinical study within the last 30 days and during this study